Mobilise-D – Mobilise-D

Connecting digital mobility assessment to clinical outcomes
for regulatory and clinical endorsement

What?

Mobilise-D is a 5-year, IMI-funded project that will produce validated and accepted digital mobility outcomes to monitor daily life gait of people with different mobility problems, with the goal to improve follow-up and personalized care.

About Us

How?

Mobilise-D will perform a technical and clinical validation of a sensor-algorithm pair in different patient groups. We maintain close dialogue with the European Medicines Agency (EMA) to facilitate the process of regulatory approval.

About Us

Who?

The Mobilise-D consortium consists of 34 partners from Europe and the USA. Over 150 professionals with technical, clinical, and regulatory expertise will work together to bring digital mobility outcomes to the clinic.

About Us

Mobility – how well we walk – is an important marker of health; a slow walking speed is associated with greater mortality, morbidity, cognitive decline, dementia, and fall risk. As the population ages, the number of people experiencing mobility challenges is expected to rise. However, accurately assessing people’s mobility, especially in the real daily life world, is far from easy.

Mobilise-D will develop a comprehensive system to monitor and evaluate people’s gait based on digital technologies, including sensors worn on the body. The project focuses on conditions which often affect mobility, namely chronic obstructive pulmonary disease, Parkinson’s disease, multiple sclerosis, hip fracture recovery, and congestive heart failure.

The Mobilise-D results will help to improve the accurate assessment of daily life mobility in clinical trials and patient treatment, thereby contributing to improved and more personalised care.

Patient Groups

Mobilise-D will focus on five different patient groups that together represent respiratory problems (chronic obstructive pulmonary disease – COPD), neurodegenerative conditions (Parkinson’s disease – PD), neuroinflammatory problems (multiple sclerosis – MS), osteoporosis and sarcopenia (hip fracture recovery/proximal femoral fracture – PFF), and cardiac pathology (congestive heart failure – CHF).

These patient groups cover a range of walking speed, mobility challenges, and potential events that we care about, such as improving versus worsening of function, falls, hospitalisation, nursing home admission, and death. Furthermore, these patient groups will be followed at 12 different sites across Europe, ensuring a good geographical representation and covering a diverse representation of health care organisation, such as in- versus outpatient care, as well as public versus private health services.

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Mobilise-D @Mobilise_D

Angelini and colleagues identified reliable gait-based #biomarkers using #wearable sensors. These may allow #clinicians to quantify clinically relevant #gait alterations in #MultipleSclerosis patients during regular clinical visits. Read more: https://t.co/V01MwCGaMC
#MobiliseD https://t.co/XTnWi7nChz

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Mobilise-D @Mobilise_D

Less than one week left to apply for this amazing opportunity to work as part of #MobiliseD! Read all about it here: https://t.co/1fb7cobDO9
@insigneo @SheffMechEng @SheffieldBRC @claudiamazza5 #GaitAnalysis #Wearables #DigitalHealth #Biomechanics #sensors #postdoc

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Latest News

VIDEO: Mobilise-D matters – now more than ever!

The large-scale social and behavioural changes that happened almost overnight in our day-to-day life due to COVID-19, illustrate the importance of anticipating and developing new ways of patient care. Especially mobility is a telling sign of how well a patient is doing. “Mobility is something that we take for granted until we lose it. And…